Nalaganje...
Genome-wide siRNA screen identifies UNC50 as a regulator of Shiga toxin 2 trafficking
Shiga toxins 1 and 2 (STx1 and STx2) undergo retrograde trafficking to reach the cytosol. Early endosome-to-Golgi transport allows the toxins to evade degradation in lysosomes. Targeting this trafficking step has therapeutic promise, but the mechanism of trafficking for the more potent toxin STx2 is...
Shranjeno v:
| izdano v: | J Cell Biol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2017
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5626549/ https://ncbi.nlm.nih.gov/pubmed/28883040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201704015 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|