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Manganese Blocks Intracellular Trafficking of Shiga Toxin and Protects Against Shiga Toxicosis
Infections with Shiga toxin (STx)–producing bacteria cause more than a million deaths each year and have no definitive treatment. To exert its cytotoxic effect, STx invades cells through retrograde membrane trafficking, escaping the lysosomal degradative pathway. We found that the widely available m...
Tallennettuna:
| Julkaisussa: | Science |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5367627/ https://ncbi.nlm.nih.gov/pubmed/22267811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1215930 |
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