NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome

Although B cell development requires expression of the B cell antigen receptor (BCR), it remains unclear whether engagement of self-antigen provides a positive impact for most B cells. Here, we show that BCR engagement by self-ligand during development in vivo results in up-regulation of the Nod-lik...

詳細記述

保存先:
書誌詳細
出版年:J Exp Med
主要な著者: Hayakawa, Kyoko, Formica, Anthony M., Zhou, Yan, Ichikawa, Daiju, Asano, Masanao, Li, Yue-Sheng, Shinton, Susan A., Brill-Dashoff, Joni, Núñez, Gabriel, Hardy, Richard R.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2017
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626402/
https://ncbi.nlm.nih.gov/pubmed/28878001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170497
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料