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FK506-binding proteins 12 and 12.6 (FKBPs) as regulators of cardiac Ryanodine Receptors: Insights from new functional and structural knowledge

Ryanodine Receptors (RyRs) are intracellular Ca(2+) channels that mediate Ca(2+) flux from the sarco(endo)plasmic reticulum in many cell types. The interaction of RyRs with FK506-binding proteins (FKBPs) has been proposed as an important regulatory mechanism, where the loss of this interaction leads...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Gonano, Luis A., Jones, Peter P.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626368/
https://ncbi.nlm.nih.gov/pubmed/28636428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2017.1344799
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