Over-expression of FK506-binding protein FKBP12.6 alters excitation–contraction coupling in adult rabbit cardiomyocytes

This study investigated the function of FK506-binding protein (FKBP12.6) using adenoviral-mediated gene transfer to over-express FKBP12.6 (Ad-FKBP12.6) in adult rabbit ventricular cardiomyocytes. Infection with a β-galactosidase-expressing adenovirus (Ad-LacZ) was used as a control. Peak-systolic in...

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Autors principals: Loughrey, C M, Seidler, T, Miller, S L W, Prestle, J, MacEachern, K E, Reynolds, D F, Hasenfuss, G, Smith, G L
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2004
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665006/
https://ncbi.nlm.nih.gov/pubmed/14966299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.057166
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