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Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain
Although a causative role of α-synuclein (α-syn) is well established in Parkinson’s disease pathogenesis, available animal models of synucleinopathy do not replicate the full range of cellular and behavioral changes characteristic of the human disease. This study was designed to generate a more fait...
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| Τόπος έκδοσης: | Proc Natl Acad Sci U S A |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625925/ https://ncbi.nlm.nih.gov/pubmed/28900002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710442114 |
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