Mutations in the E2 Glycoprotein and the 3′ Untranslated Region Enhance Chikungunya Virus Virulence in Mice

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection. Although studies of humans and experimentally infected animals suggest that CHIKV infection persists in musculoskel...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hawman, David W., Carpentier, Kathryn S., Fox, Julie M., May, Nicholas A., Sanders, Wes, Montgomery, Stephanie A., Moorman, Nathaniel J., Diamond, Michael S., Morrison, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625495/
https://ncbi.nlm.nih.gov/pubmed/28747508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00816-17
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