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Mutations in the E2 Glycoprotein and the 3′ Untranslated Region Enhance Chikungunya Virus Virulence in Mice

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection. Although studies of humans and experimentally infected animals suggest that CHIKV infection persists in musculoskel...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Hawman, David W., Carpentier, Kathryn S., Fox, Julie M., May, Nicholas A., Sanders, Wes, Montgomery, Stephanie A., Moorman, Nathaniel J., Diamond, Michael S., Morrison, Thomas E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625495/
https://ncbi.nlm.nih.gov/pubmed/28747508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00816-17
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