Potent In Vivo NK Cell-Mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-Bispecific and Hexavalent Broadly Neutralizing Fusion Protein

Antibodies bound to human immunodeficiency virus type 1 (HIV-1) envelope protein expressed by infected cells mobilize antibody-dependent cellular cytotoxicity (ADCC) to eliminate the HIV-1-infected cells and thereby suppress HIV-1 infection and delay disease progression. Studies treating HIV-1-infec...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Bardhi, Ariola, Wu, Yanling, Chen, Weizao, Li, Wei, Zhu, Zhongyu, Zheng, Jian Hua, Wong, Hing, Jeng, Emily, Jones, Jennifer, Ochsenbauer, Christina, Kappes, John C., Dimitrov, Dimiter S., Ying, Tianlei, Goldstein, Harris
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Cellular Response to Infection
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625480/
https://ncbi.nlm.nih.gov/pubmed/28794022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00937-17
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