Vitamin D Counteracts an IL-23–Dependent IL-17A(+)IFN-γ(+) Response Driven by Urban Particulate Matter

Urban particulate matter (UPM) air pollution and vitamin D deficiency are detrimentally associated with respiratory health. This is hypothesized to be due in part to regulation of IL-17A, which UPM is reported to promote. Here, we used a myeloid dendritic cell (DC)-memory CD4(+) T cell co-culture sy...

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Vydáno v:Am J Respir Cell Mol Biol
Hlavní autoři: Mann, Elizabeth H., Ho, Tzer-Ren, Pfeffer, Paul E., Matthews, Nick C., Chevretton, Elfy, Mudway, Ian, Kelly, Frank J., Hawrylowicz, Catherine M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625227/
https://ncbi.nlm.nih.gov/pubmed/28463086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0409OC
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