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IL-23 modulated myelin-specific T cells induce EAE via an IFNγ driven, IL-17 independent pathway

Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system (CNS) mediated by myelin-reactive CD4(+) T cells. An unresolved issue that has important clinical implications concerns the cytokines produced by myelin-reactive T cells that determ...

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Detalhes bibliográficos
Main Authors: Kroenke, Mark A., Segal, Benjamin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064959/
https://ncbi.nlm.nih.gov/pubmed/20951792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2010.10.001
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