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Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease

Huntington's disease (HD) is an autosomal dominant, neurodegenerative disorder characterized by motor as well as nonmotor symptoms for which there is currently no cure. The Q175 mouse model of HD recapitulates many of the symptoms identified in HD patients including disruptions of the sleep/wak...

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Dades bibliogràfiques
Publicat a:Pharmacol Res Perspect
Autors principals: Whittaker, Daniel S., Wang, Huei‐Bin, Loh, Dawn H., Cachope, Roger, Colwell, Christopher S.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625154/
https://ncbi.nlm.nih.gov/pubmed/28971617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.344
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