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Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease

Huntington's disease (HD) is an autosomal dominant, neurodegenerative disorder characterized by motor as well as nonmotor symptoms for which there is currently no cure. The Q175 mouse model of HD recapitulates many of the symptoms identified in HD patients including disruptions of the sleep/wak...

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Detaylı Bibliyografya
Yayımlandı:Pharmacol Res Perspect
Asıl Yazarlar: Whittaker, Daniel S., Wang, Huei‐Bin, Loh, Dawn H., Cachope, Roger, Colwell, Christopher S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625154/
https://ncbi.nlm.nih.gov/pubmed/28971617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.344
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