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Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease

Huntington's disease (HD) is an autosomal dominant, neurodegenerative disorder characterized by motor as well as nonmotor symptoms for which there is currently no cure. The Q175 mouse model of HD recapitulates many of the symptoms identified in HD patients including disruptions of the sleep/wak...

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Bibliografische gegevens
Gepubliceerd in:Pharmacol Res Perspect
Hoofdauteurs: Whittaker, Daniel S., Wang, Huei‐Bin, Loh, Dawn H., Cachope, Roger, Colwell, Christopher S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625154/
https://ncbi.nlm.nih.gov/pubmed/28971617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.344
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