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The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase

PURPOSE: While nitric oxide (NO) donors are emerging as treatments for glaucoma, the mechanism by which NO lowers intraocular pressure (IOP) is unclear. NO activates the enzyme guanylyl cyclase (GC) to produce cyclic guanosine monophosphate. We studied the ocular effects of inhaled and topically app...

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Detaylı Bibliyografya
Yayımlandı:Invest Ophthalmol Vis Sci
Asıl Yazarlar: Muenster, Stefan, Lieb, Wolfgang S., Fabry, Gregor, Allen, Kaitlin N., Kamat, Shivani S., Guy, Ann H., Dordea, Ana C., Teixeira, Leandro, Tainsh, Robert E., Yu, Binglan, Zhu, Wei, Ashpole, Nicole E., Malhotra, Rajeev, Brouckaert, Peter, Bloch, Donald B., Scherrer-Crosbie, Marielle, Stamer, W. Daniel, Kuehn, Markus H., Pasquale, Louis R., Buys, Emmanuel S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Association for Research in Vision and Ophthalmology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624778/
https://ncbi.nlm.nih.gov/pubmed/28973329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22168
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