Residues in the eighth transmembrane domain of the proton-coupled folate transporter (SLC46A1) play an important role in defining the aqueous translocation pathway and in folate substrate binding

Antzeko izenburuak

• Hereditary folate malabsorption due to a mutation in the external gate of the proton-coupled folate transporter SLC46A1
  nork: Aluri, Srinivas, et al.
  Argitaratua: (2018)
• Substituted-cysteine accessibility and cross-linking identify an exofacial cleft in the 7th and 8th helices of the proton-coupled folate transporter (SLC46A1)
  nork: Aluri, Srinivas, et al.
  Argitaratua: (2018)
• Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation
  nork: Aluri, Srinivas, et al.
  Argitaratua: (2019)
• The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption
  nork: Zhao, Rongbao, et al.
  Argitaratua: (2016)
• The Functional Roles of the His(247) and His(281) Residues in Folate and Proton Translocation Mediated by the Human Proton-coupled Folate Transporter SLC46A1
  nork: Unal, Ersin Selcuk, et al.
  Argitaratua: (2009)