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Carcinogen susceptibility is regulated by genome architecture and predicts cancer mutagenesis
The development of many sporadic cancers is directly initiated by carcinogen exposure. Carcinogens induce malignancies by creating DNA lesions (i.e., adducts) that can result in mutations if left unrepaired. Despite this knowledge, there has been remarkably little investigation into the regulation o...
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| Publicado no: | EMBO J |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5623849/ https://ncbi.nlm.nih.gov/pubmed/28814448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796717 |
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