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Manifold Based Optimization for Single-Cell 3D Genome Reconstruction
The three-dimensional (3D) structure of the genome is important for orchestration of gene expression and cell differentiation. While mapping genomes in 3D has for a long time been elusive, recent adaptations of high-throughput sequencing to chromosome conformation capture (3C) techniques, allows for...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532452/ https://ncbi.nlm.nih.gov/pubmed/26262780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004396 |
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