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Insight into the Selectivity of the G7-18NATE Inhibitor Peptide for the Grb7-SH2 Domain Target
Growth factor receptor bound protein 7 (Grb7) is an adaptor protein with established roles in the progression of both breast and pancreatic cancers. Through its C-terminal SH2 domain, Grb7 binds to phosphorylated tyrosine kinases to promote proliferative and migratory signaling. Here, we investigate...
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Vydáno v: | Front Mol Biosci |
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Hlavní autoři: | , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Frontiers Media S.A.
2017
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5623053/ https://ncbi.nlm.nih.gov/pubmed/29018805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2017.00064 |
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