Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target

Antiphospholipid antibodies, present in one-third of lupus patients, increase the risk of thrombosis. We recently reported a key role for neutrophils — neutrophil extracellular traps (NETs), in particular — in the thrombotic events that define antiphospholipid syndrome (APS). To further elucidate th...

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Vydáno v:JCI Insight
Hlavní autoři: Knight, Jason S., Meng, He, Coit, Patrick, Yalavarthi, Srilakshmi, Sule, Gautam, Gandhi, Alex A., Grenn, Robert C., Mazza, Levi F., Ali, Ramadan A., Renauer, Paul, Wren, Jonathan D., Bockenstedt, Paula L., Wang, Hui, Eitzman, Daniel T., Sawalha, Amr H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621930/
https://ncbi.nlm.nih.gov/pubmed/28931754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93897
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