Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target

Antiphospholipid antibodies, present in one-third of lupus patients, increase the risk of thrombosis. We recently reported a key role for neutrophils — neutrophil extracellular traps (NETs), in particular — in the thrombotic events that define antiphospholipid syndrome (APS). To further elucidate th...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Knight, Jason S., Meng, He, Coit, Patrick, Yalavarthi, Srilakshmi, Sule, Gautam, Gandhi, Alex A., Grenn, Robert C., Mazza, Levi F., Ali, Ramadan A., Renauer, Paul, Wren, Jonathan D., Bockenstedt, Paula L., Wang, Hui, Eitzman, Daniel T., Sawalha, Amr H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621930/
https://ncbi.nlm.nih.gov/pubmed/28931754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93897
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