Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target

Antiphospholipid antibodies, present in one-third of lupus patients, increase the risk of thrombosis. We recently reported a key role for neutrophils — neutrophil extracellular traps (NETs), in particular — in the thrombotic events that define antiphospholipid syndrome (APS). To further elucidate th...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Knight, Jason S., Meng, He, Coit, Patrick, Yalavarthi, Srilakshmi, Sule, Gautam, Gandhi, Alex A., Grenn, Robert C., Mazza, Levi F., Ali, Ramadan A., Renauer, Paul, Wren, Jonathan D., Bockenstedt, Paula L., Wang, Hui, Eitzman, Daniel T., Sawalha, Amr H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621930/
https://ncbi.nlm.nih.gov/pubmed/28931754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93897
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