Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target

Antiphospholipid antibodies, present in one-third of lupus patients, increase the risk of thrombosis. We recently reported a key role for neutrophils — neutrophil extracellular traps (NETs), in particular — in the thrombotic events that define antiphospholipid syndrome (APS). To further elucidate th...

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Publicado en:JCI Insight
Autores principales: Knight, Jason S., Meng, He, Coit, Patrick, Yalavarthi, Srilakshmi, Sule, Gautam, Gandhi, Alex A., Grenn, Robert C., Mazza, Levi F., Ali, Ramadan A., Renauer, Paul, Wren, Jonathan D., Bockenstedt, Paula L., Wang, Hui, Eitzman, Daniel T., Sawalha, Amr H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621930/
https://ncbi.nlm.nih.gov/pubmed/28931754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93897
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