Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target

Antiphospholipid antibodies, present in one-third of lupus patients, increase the risk of thrombosis. We recently reported a key role for neutrophils — neutrophil extracellular traps (NETs), in particular — in the thrombotic events that define antiphospholipid syndrome (APS). To further elucidate th...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Knight, Jason S., Meng, He, Coit, Patrick, Yalavarthi, Srilakshmi, Sule, Gautam, Gandhi, Alex A., Grenn, Robert C., Mazza, Levi F., Ali, Ramadan A., Renauer, Paul, Wren, Jonathan D., Bockenstedt, Paula L., Wang, Hui, Eitzman, Daniel T., Sawalha, Amr H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621930/
https://ncbi.nlm.nih.gov/pubmed/28931754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93897
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