Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer

Checkpoint inhibitors have demonstrated efficacy in patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). However, the majority of patients do not benefit from these agents. To improve the efficacy of checkpoint inhibitors, intratumoral (i.t.) injection with innate imm...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:JCI Insight
Κύριοι συγγραφείς: Sato-Kaneko, Fumi, Yao, Shiyin, Ahmadi, Alast, Zhang, Shannon S., Hosoya, Tadashi, Kaneda, Megan M., Varner, Judith A., Pu, Minya, Messer, Karen S., Guiducci, Cristiana, Coffman, Robert L., Kitaura, Kazutaka, Matsutani, Takaji, Suzuki, Ryuji, Carson, Dennis A., Hayashi, Tomoko, Cohen, Ezra E.W.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2017
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621908/
https://ncbi.nlm.nih.gov/pubmed/28931759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93397
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