NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B(4) Synthesis

Rationale: Sepsis, a life-threatening organ dysfunction caused by a dysregulated host response to infection, is a major public health concern with high mortality and morbidity. Although inflammatory responses triggered by infection are crucial for host defense against invading microbes, the excessiv...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Lee, Seonmin, Nakahira, Kiichi, Dalli, Jesmond, Siempos, Ilias I., Norris, Paul C., Colas, Romain A., Moon, Jong-Seok, Shinohara, Masakazu, Hisata, Shu, Howrylak, Judie Ann, Suh, Gee-Young, Ryter, Stefan W., Serhan, Charles N., Choi, Augustine M. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620673/
https://ncbi.nlm.nih.gov/pubmed/28245134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201604-0892OC
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