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NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B(4) Synthesis
Rationale: Sepsis, a life-threatening organ dysfunction caused by a dysregulated host response to infection, is a major public health concern with high mortality and morbidity. Although inflammatory responses triggered by infection are crucial for host defense against invading microbes, the excessiv...
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Pubblicato in: | Am J Respir Crit Care Med |
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Autori principali: | , , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Thoracic Society
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5620673/ https://ncbi.nlm.nih.gov/pubmed/28245134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201604-0892OC |
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