Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations

Extensive genomic profiling for endometrioid endometrial carcinoma (EEC) has pointed to genes and pathways important in uterine development as critical mediators of endometrial tumorigenesis. SOX17 is a developmental transcription factor necessary for proper endoderm formation that has been implicat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Walker, Christopher J., O'Hern, Matthew J., Serna, Vanida A., Kurita, Takeshi, Miranda, Mario A., Sapp, Caroline E., Mutch, David G., Cohn, David E., Goodfellow, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620294/
https://ncbi.nlm.nih.gov/pubmed/28978154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20213
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