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Patterns of CTCF and ZFHX3 Mutation and Associated Outcomes in Endometrial Cancer

BACKGROUND: The genetic events responsible for tumor aggressiveness in endometrioid endometrial cancer (EEC) remain poorly understood. The chromosome 16q22 tumor suppressor genes CTCF and ZFHX3 are both frequently mutated in EEC, but their respective roles in outcome have not been determined. METHOD...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Walker, Christopher J., Miranda, Mario A., O’Hern, Matthew J., McElroy, Joseph P., Coombes, Kevin R., Bundschuh, Ralf, Cohn, David E., Mutch, David G., Goodfellow, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643635/
https://ncbi.nlm.nih.gov/pubmed/26330387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv249
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