MAX Mutations in Endometrial Cancer: Clinicopathologic Associations and Recurrent MAX p.His28Arg Functional Characterization

BACKGROUND: Genomic studies have revealed that multiple genes are mutated at varying frequency in endometrial cancer (EC); however, the relevance of many of these mutations is poorly understood. An EC-specific recurrent mutation in the MAX transcription factor p.His28Arg was recently discovered. We...

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Veröffentlicht in:J Natl Cancer Inst
Hauptverfasser: Walker, Christopher J, Rush, Craig M, Dama, Paola, O’Hern, Matthew J, Cosgrove, Casey M, Gillespie, Jessica L, Zingarelli, Roman A, Smith, Blair, Stein, Maggie E, Mutch, David G, Shakya, Reena, Chang, Chia-Wen, Selvendiran, Karuppaiyah, Song, Jonathan W, Cohn, David E, Goodfellow, Paul J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279289/
https://ncbi.nlm.nih.gov/pubmed/29155953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx238
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