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High frequency strand slippage mutations in CTCF in MSI-positive endometrial cancers
Tumors with defective mismatch repair acquire large numbers of strand slippage mutations including frameshifts in coding sequence repeats. We identified a mutational hotspot, p.T204fs, in the insulator-binding protein (CTCF) in MSI-positive endometrial cancers. Although CTCF was described as a signi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946358/ https://ncbi.nlm.nih.gov/pubmed/24130125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22463 |
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