Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux

Carboxypeptidase E (CPE) has recently been described as a multifunctional protein that regulates proliferation, migration and survival in several tumor entities. In glioblastoma (GBM), the most malignant primary brain tumor, secreted CPE (sCPE) was shown to modulate tumor cell migration. In our curr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ilina, Elena I., Armento, Angela, Sanchez, Leticia Garea, Reichlmeir, Marina, Braun, Yannick, Penski, Cornelia, Capper, David, Sahm, Felix, Jennewein, Lukas, Harter, Patrick N., Zukunft, Sven, Fleming, Ingrid, Schulte, Dorothea, Le Guerroué, Francois, Behrends, Christian, Ronellenfitsch, Michael W., Naumann, Ulrike, Mittelbronn, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620194/
https://ncbi.nlm.nih.gov/pubmed/28978054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18747
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