Clostridium Perfringens Enterotoxin (CPE) and CPE-Binding Domain (c-CPE) for the Detection and Treatment of Gynecologic Cancers

Clostridium perfringens enterotoxin (CPE) is a three-domain polypeptide, which binds to Claudin-3 and Claudin-4 with high affinity. Because these receptors are highly differentially expressed in many human tumors, claudin-3 and claudin-4 may provide an efficient molecular tool to specifically identi...

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Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Black, Jonathan D., Lopez, Salvatore, Cocco, Emiliano, Schwab, Carlton L., English, Diana P., Santin, Alessandro D.
Format: Artigo
Language:Inglês
Published: MDPI 2015
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417958/
https://ncbi.nlm.nih.gov/pubmed/25835384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7041116
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