Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis

Monocytes are innate immune cells that play a pivotal role in antifungal immunity, but little is known regarding the cellular metabolic events that regulate their function during infection. Using complementary transcriptomic and immunological studies in human primary monocytes, we show that activati...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Domínguez-Andrés, Jorge, Arts, Rob J. W., ter Horst, Rob, Gresnigt, Mark S., Smeekens, Sanne P., Ratter, Jacqueline M., Lachmandas, Ekta, Boutens, Lily, van de Veerdonk, Frank L., Joosten, Leo A. B., Notebaart, Richard A., Ardavín, Carlos, Netea, Mihai G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619837/
https://ncbi.nlm.nih.gov/pubmed/28922415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006632
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