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Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37
The effect of the anti-inflammatory cytokine interleukin-37 (IL-37) on host defense against Candida infections remains unknown. We assessed the role of IL-37 in a murine model of disseminated candidiasis using mice transgenic for human IL-37 (hIL-37Tg). Upon exposure to Candida albicans pseudohyphae...
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| Publicado no: | Front Microbiol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285810/ https://ncbi.nlm.nih.gov/pubmed/25620965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00762 |
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