The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis

The Nlrp3 inflammasome has been proposed to play an important role in antifungal host defense. However, studies exploring the role of the inflammasome in antifungal host defense have been limited to the direct effects on IL-1β processing. Although IL-1β has important direct effects on the innate imm...

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Hlavní autoři: van de Veerdonk, Frank L., Joosten, Leo A.B., Shaw, Patrick J., Smeekens, Sanne P., Malireddi, Subbarao, van der Meer, Jos W.M., Kullberg, Bart-Jan, Netea, Mihai G., Kanneganti, Thirumala-Devi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939807/
https://ncbi.nlm.nih.gov/pubmed/21681738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041226
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