Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism

Borrelia burgdorferi spirochetes cause Lyme Disease, which can result in severe clinical symptoms such as multiple joint inflammation and neurological disorders. IFN-γ and IL-17 have been suggested to play an important role in the host defense against Borrelia, and in the immunopathology of Lyme Dis...

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Main Authors: Oosting, Marije, van de Veerdonk, Frank L., Kanneganti, Thirumala-Devi, Sturm, Patrick, Verschueren, Ineke, Berende, Anneleen, van der Meer, Jos W.M., Kullberg, Bart-Jan, Netea, Mihai G., Joosten, Leo A.B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939779/
https://ncbi.nlm.nih.gov/pubmed/21182088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040385
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