Autophagy Modulates Borrelia burgdorferi-induced Production of Interleukin-1β (IL-1β)

Borrelia burgdorferi sensu lato is the causative agent of Lyme disease. Recent studies have shown that recognition of the spirochete is mediated by TLR2 and NOD2. The latter receptor has been associated with the induction of the intracellular degradation process called autophagy. The present study d...

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Main Authors: Buffen, Kathrin, Oosting, Marije, Mennens, Svenja, Anand, Paras K., Plantinga, Theo S., Sturm, Patrick, van de Veerdonk, Frank L., van der Meer, Jos W. M., Xavier, Ramnik J., Kanneganti, Thirumala-Devi, Netea, Mihai G., Joosten, Leo A. B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605684/
https://ncbi.nlm.nih.gov/pubmed/23386602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412841
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