Autophagy Modulates Borrelia burgdorferi-induced Production of Interleukin-1β (IL-1β)

Borrelia burgdorferi sensu lato is the causative agent of Lyme disease. Recent studies have shown that recognition of the spirochete is mediated by TLR2 and NOD2. The latter receptor has been associated with the induction of the intracellular degradation process called autophagy. The present study d...

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Hauptverfasser: Buffen, Kathrin, Oosting, Marije, Mennens, Svenja, Anand, Paras K., Plantinga, Theo S., Sturm, Patrick, van de Veerdonk, Frank L., van der Meer, Jos W. M., Xavier, Ramnik J., Kanneganti, Thirumala-Devi, Netea, Mihai G., Joosten, Leo A. B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605684/
https://ncbi.nlm.nih.gov/pubmed/23386602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412841
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