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Sequence-Dependent Self-Assembly and Structural Diversity of Islet Amyloid Polypeptide-Derived β-Sheet Fibrils

[Image: see text] Determining the structural origins of amyloid fibrillation is essential for understanding both the pathology of amyloidosis and the rational design of inhibitors to prevent or reverse amyloid formation. In this work, the decisive roles of peptide structures on amyloid self-assembly...

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Библиографические подробности
Опубликовано в: :ACS Nano
Главные авторы: Wang, Shih-Ting, Lin, Yiyang, Spencer, Ryan K., Thomas, Michael R., Nguyen, Andy I., Amdursky, Nadav, Pashuck, E. Thomas, Skaalure, Stacey C., Song, Cheng Yu, Parmar, Paresh A., Morgan, Rhodri M., Ercius, Peter, Aloni, Shaul, Zuckermann, Ronald N., Stevens, Molly M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2017
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618150/
https://ncbi.nlm.nih.gov/pubmed/28771324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b02325
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