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MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology
Cystic fibrosis results from reduced cystic fibrosis transmembrane conductance regulator protein activity leading to defective epithelial ion transport. Ca(2+)-activated Cl(−) channels mediate physiological functions independently of cystic fibrosis transmembrane conductance regulator. Anoctamin 1 (...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617894/ https://ncbi.nlm.nih.gov/pubmed/28955034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00813-z |
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