Opposite Expression of Hepatic and Pulmonary Corticosteroid-Binding Globulin in Cystic Fibrosis Patients

Cystic fibrosis (CF) is characterized by a chronic pulmonary inflammation. In CF, glucocorticoids (GC) are widely used, but their efficacy and benefit/risk ratio are still debated. In plasma, corticosteroid-binding globulin (CBG) binds 90% of GC and delivers them to the inflammatory site. The main g...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Tchoukaev, Anastasia, Taytard, Jessica, Rousselet, Nathalie, Rebeyrol, Carine, Debray, Dominique, Blouquit-Laye, Sabine, Moisan, Marie-Pierre, Foury, Aline, Guillot, Loic, Corvol, Harriet, Tabary, Olivier, Le Rouzic, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996105/
https://ncbi.nlm.nih.gov/pubmed/29922157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00545
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