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C1-Ten is a PTPase of nephrin, regulating podocyte hypertrophy through mTORC1 activation
Hypertrophy is a prominent feature of damaged podocytes in diabetic kidney disease (DKD). mTORC1 hyperactivation leads to podocyte hypertrophy, but the detailed mechanism of how mTORC1 activation occurs under pathological conditions is not completely known. Moreover, reduced nephrin tyrosine phospho...
Uloženo v:
| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617844/ https://ncbi.nlm.nih.gov/pubmed/28955049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12382-8 |
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