Hemopexin Induces Nephrin-Dependent Reorganization of the Actin Cytoskeleton in Podocytes

Hemopexin is an abundant plasma protein that effectively scavenges heme. When infused into rats, hemopexin induces reversible proteinuria, and activated hemopexin is increased in children with minimal change nephrotic syndrome. These observations suggest a role for hemopexin in glomerular disease; i...

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Main Authors: Lennon, Rachel, Singh, Anurag, Welsh, Gavin I., Coward, Richard J., Satchell, Simon, Ni, Lan, Mathieson, Peter W., Bakker, Winston W., Saleem, Moin A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2008
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573012/
https://ncbi.nlm.nih.gov/pubmed/18753258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007080940
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