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Co-Localization of Nephrin, Podocin, and the Actin Cytoskeleton : Evidence for a Role in Podocyte Foot Process Formation

The discovery of the genes for nephrin and podocin, which are mutated in two types of congenital nephrotic syndrome, was pivotal in establishing the podocyte as the central component of the glomerular filtration barrier. In vivo the proteins have been localized to the podocyte slit diaphragm, and th...

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Autori principali: Saleem, Moin A., Ni, Lan, Witherden, Ian, Tryggvason, Karl, Ruotsalainen, Vesa, Mundel, Peter, Mathieson, Peter W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867300/
https://ncbi.nlm.nih.gov/pubmed/12368218
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