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C1-Ten is a PTPase of nephrin, regulating podocyte hypertrophy through mTORC1 activation
Hypertrophy is a prominent feature of damaged podocytes in diabetic kidney disease (DKD). mTORC1 hyperactivation leads to podocyte hypertrophy, but the detailed mechanism of how mTORC1 activation occurs under pathological conditions is not completely known. Moreover, reduced nephrin tyrosine phospho...
Gorde:
| Argitaratua izan da: | Sci Rep |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617844/ https://ncbi.nlm.nih.gov/pubmed/28955049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12382-8 |
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