Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice

BRCA deficiency predisposes to the development of invasive breast cancer. In BRCA mutation carriers this risk can increase up to 80%. Currently, bilateral prophylactic mastectomy and prophylactic bilateral salpingo-oophorectomy are the only preventive, albeit radical invasive strategies to prevent b...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: de Groot, Jolien S., van Diest, Paul J., van Amersfoort, Miranda, Vlug, Eva J., Pan, Xiaojuan, ter Hoeve, Natalie D., Rosing, Hilde, Beijnen, Jos H., Youssef, Sameh A., de Bruin, Alain, Jonkers, Jos, van der Wall, Elsken, Derksen, Patrick W.B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617383/
https://ncbi.nlm.nih.gov/pubmed/28977823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18490
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares