A proteomic atlas of insulin signalling reveals tissue‐specific mechanisms of longevity assurance

Lowered activity of the insulin/IGF signalling (IIS) network can ameliorate the effects of ageing in laboratory animals and, possibly, humans. Although transcriptome remodelling in long‐lived IIS mutants has been extensively documented, the causal mechanisms contributing to extended lifespan, partic...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Syst Biol
Main Authors: Tain, Luke S, Sehlke, Robert, Jain, Chirag, Chokkalingam, Manopriya, Nagaraj, Nagarjuna, Essers, Paul, Rassner, Mark, Grönke, Sebastian, Froelich, Jenny, Dieterich, Christoph, Mann, Matthias, Alic, Nazif, Beyer, Andreas, Partridge, Linda
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615923/
https://ncbi.nlm.nih.gov/pubmed/28916541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177663
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki