A proteomic atlas of insulin signalling reveals tissue‐specific mechanisms of longevity assurance

Lowered activity of the insulin/IGF signalling (IIS) network can ameliorate the effects of ageing in laboratory animals and, possibly, humans. Although transcriptome remodelling in long‐lived IIS mutants has been extensively documented, the causal mechanisms contributing to extended lifespan, partic...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Tain, Luke S, Sehlke, Robert, Jain, Chirag, Chokkalingam, Manopriya, Nagaraj, Nagarjuna, Essers, Paul, Rassner, Mark, Grönke, Sebastian, Froelich, Jenny, Dieterich, Christoph, Mann, Matthias, Alic, Nazif, Beyer, Andreas, Partridge, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615923/
https://ncbi.nlm.nih.gov/pubmed/28916541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177663
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