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Ultrasensitive Measurement of Ca(2+) Influx into Lipid Vesicles Induced by Protein Aggregates
To quantify and characterize the potentially toxic protein aggregates associated with neurodegenerative diseases, a high‐throughput assay based on measuring the extent of aggregate‐induced Ca(2+) entry into individual lipid vesicles has been developed. This approach was implemented by tethering vesi...
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| Wydane w: | Angew Chem Int Ed Engl |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5615231/ https://ncbi.nlm.nih.gov/pubmed/28474754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201700966 |
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