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Selecting Optimal Peptides for Targeted Proteomic Experiments in Human Plasma Using in vitro Synthesized Proteins as Analytical Standards

In targeted proteomics, the development of robust methodologies is dependent upon the selection of a set of optimal peptides for each protein-of-interest. Unfortunately, predicting which peptides and respective product ion transitions provide the greatest signal-to-noise ratio in a particular assay...

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Publicat a:Methods Mol Biol
Autors principals: Bollinger, James G., Stergachis, Andrew B., Johnson, Richard S., Egertson, Jarrett D., MacCoss, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614897/
https://ncbi.nlm.nih.gov/pubmed/26867746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3524-6_12
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