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Using Data Independent Acquisition (DIA) to Model High-responding Peptides for Targeted Proteomics Experiments

Targeted mass spectrometry is an essential tool for detecting quantitative changes in low abundant proteins throughout the proteome. Although selected reaction monitoring (SRM) is the preferred method for quantifying peptides in complex samples, the process of designing SRM assays is laborious. Pept...

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Détails bibliographiques
Publié dans:Mol Cell Proteomics
Auteurs principaux: Searle, Brian C., Egertson, Jarrett D., Bollinger, James G., Stergachis, Andrew B., MacCoss, Michael J.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563719/
https://ncbi.nlm.nih.gov/pubmed/26100116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.051300
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