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Hyperexcitability in synaptic and firing activities of spinal motoneurons in an adult mouse model of amyotrophic lateral sclerosis

Hyperexcitability is hypothesized to contribute to the degeneration of spinal motoneurons (MNs) in amyotrophic lateral sclerosis (ALS). Studies, thus far, have not linked hyperexcitability to the intrinsic properties of MNs in the adult ALS mouse model with the G93A-mutated SOD1 protein (mSOD1(G93A)...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Jiang, Mingchen C., Adimula, Adesoji, Birch, Derin, Heckman, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614896/
https://ncbi.nlm.nih.gov/pubmed/28844763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.08.041
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